Search Results - ahmed chadli

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Novel Hsp90 Inhibitors for Breast Cancer Treatment
TitleNovel Hsp90 Inhibitors for Breast Cancer TreatmentPresent State of the ArtHsp90 (heat shock proteins) are popular cancer drug targets due to their anti-apoptotic activities. Several classes of Hsp90 inhibitors are in clinical trial.Problem of the Present ArtHsp90 inhibitors are often successful in diminishing or deactivating the Hsp90 in the c...
Published: 8/13/2019   |   Inventor(s): Ahmed Chadli, Abdessamad Debbab, Peter Proksch
Keywords(s):  
Category(s): Therapeutics
Combinatorial Therapeutic for Breast and Prostate Cancer Treatments
Title Combinatorial Therapeutic for Breast and Prostate Cancer TreatmentsPresent State of the ArtHsp90 (heat shock proteins) are popular cancer drug targets due to their anti-apoptotic activities. Several classes of Hsp90 inhibitors are in clinical trial.Problem of the Present ArtHsp90 inhibitors are often successful in diminishing or deactivating ...
Published: 8/13/2019   |   Inventor(s): Ahmed Chadli, Chaitanya Anil Patwardhan
Keywords(s):  
Category(s): Therapeutics
Enniatin A as a Novel Hsp90 Machine Inhibitor Combining Cancer Cell Toxicity and Immunotherapy
AU researchers have developed a unique high throughput screen (HTS) based on the progesterone receptor (PR) and the five components of the Hsp90 machine. During their preliminary screening of natural products , they discovered that the cyclic peptide Enniatin A (EnnA) kills cancer cells through inhibition of the Hsp90 machine without a significant ...
Published: 3/12/2018   |   Inventor(s): Ahmed Chadli
Keywords(s):  
Category(s): Therapeutics
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