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Deep Brain Stimulation for the Treatment of Non-Alzheimer's Dementia

The current state of the art The current treatment option for Alzheimer’s disease and aging related dementia are focused on the alleviation of symptoms and managing cognition. Degeneration of cholinergic neurons is one of the mechanisms leading to cognition declination. Therefore, aging and Alzheimer’s dementia is commonly treated with...

Published: 4/7/2023 | Inventor(s): Cole Giller, David Blake, David Hess, Alvin Terry, Jr., John Morgan, Gregory Lee, Jonathan Crawford, Ruifeng Liu, Christos Constantinidis

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Category(s): Therapeutics

Novel Analogs of Choline for Neuroprotection and Cognitive Enhancement in Neurodegenerative Disorders

Current State of the Art: Acetylcholine neurotransmission in the peripheral and central nervous system is responsible for autonomic function (heart beating, breathing) and cognitive skills including working memory, muscle. Degeneration of the nervous system and/or cognitive dysfunction/impairment are associated with a variety of neurological...

Published: 1/29/2013 | Inventor(s): Jerry Buccafusco, Alvin Terry, Jr., J. Warren Beach, Ramamohana Jonnala

Keywords(s):

Category(s): Therapeutics