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Novel TREM1 inhibitor for pathological inflammatory response

The current state of the art Trigging receptor expressed on myeloid cell 1 (TREM-1) plays a critical role in the pathogenesis of acute and chronic cardiovascular conditions, and is a crucial mediator of septic shock, especially, in cytokine release syndrome. Inhibiting TREM-1 is a promising therapeutic candidate for TREM-related diseases such as inflammatory...

Published: 4/7/2023 | Inventor(s): Anatolij Horuzsko, Iryna Lebedyeva, Thomas Albers, Ashwin Ajith

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Category(s): Therapeutics