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CAR-T cell compositions and use in hepatocellular carcinoma
The current state of the art The majority of liver cancers, the 2nd leading cause of cancer death among adult men, are hepatocellular carcinoma (HCC). About 70-80% HCC tumors, but not normal hepatocytes, express glypican 3 (GPC3), a cell surface antigen. Thus, GPC3 might be a great target for HCC immunotherapy, especially chimeric antigen receptor-modified...
Published: 7/1/2022   |   Inventor(s): Yukai He, Xiaotao Jiang, Leidy Caraballo Galva, Xiangguo Qiu
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Category(s): Therapeutics
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