Search Results - gurmukh+singh

2 Results

Sort By:

Crosslinking proteins to RBCs (protein-RBCs) with EDC can be improved with sulfo-NHS +/- sulfo-NHS-acetate

Intravenous infusion of protein/peptide antigens linked to lymphocytes with ethylene carbodiimide (EDC) is a highly efficient method for inducing peripheral, antigen-specific T cell tolerance for the treatment of autoimmune disease. Likewise, red blood cells (RBC) can be used to deliver protein/peptide antigens for treatment of autoimmune disease. EDC...

Published: 7/11/2023 | Inventor(s): Ryan Jajosky, Rafal Pacholczyk, Gurmukh Singh

Keywords(s):

Category(s): Therapeutics

Quantification by Ultrafiltration and Immunofixation Electrophoresis Testing (QUIET) for monoclonal serum free light chains

The current state of the art: Plasma cell myelomas is a plasma cell disorder that is associated with the presence of monoclonal immunoglobulin or fragments secreted by a B-cell clone. It can be detected and monitored by the presence of free monoclonal light chains. Currently, the serum free-light-chain (sFLC) assay is the most analytically sensitive...

Published: 4/7/2023 | Inventor(s): Gurmukh Singh, Roni Bollag

Keywords(s):

Category(s): Diagnostics, Methods, Research Tools