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Blockchain Technology with Hybrid Models: Health Analytics and Pre-emptive Therapy options to save patients
The current state of the art:Healthcare-associated infection (HAI) places a significant burden on the patients and the health care system. It is estimated that 3% of hospitalized patients had one or more HAI in 2015. It accounts for about 1.7 million infections and 99,000 death per year. On the other hand, the Centers for Medicare and Medicaid Services...
Published: 3/6/2020   |   Inventor(s): Arni Rao, Jose Vazquez, Luis Ostrosky
Keywords(s):  
Category(s): Diagnostics
Quantification by Ultrafiltration and Immunofixation Electrophoresis Testing (QUIET) for monoclonal serum free light chains
The current state of the art: Plasma cell myelomas is a plasma cell disorder that is associated with the presence of monoclonal immunoglobulin or fragments secreted by a B-cell clone. It can be detected and monitored by the presence of free monoclonal light chains. Currently, the serum free-light-chain (sFLC) assay is the most analytically sensitive...
Published: 12/19/2019   |   Inventor(s): Gurmukh Singh, Roni Bollag
Keywords(s):  
Category(s): Diagnostics, Methods, Research Tools
A Transcriptomic Classifier of Gliomas
The current state of the art:Gliomas account for about 27% of all brain tumors and about 80% of the malignant tumors. Currently, Glioma is classified by histology and the gene mutation test (isocitrate dehydrogenase, IDH) defined by the world health organization (WHO).The problems with the current art:However, there is a big discrepancy between histology...
Published: 12/17/2019   |   Inventor(s): Jin-Xiong She, Paul Tran
Keywords(s):  
Category(s): Diagnostics
Biomarkers for Therapeutic Monitoring of Ovarian Cancer
A method for assessing therapeutic outcome of a treatment for ovarian cancer comprising determining the amount of one or more proteins in a blood sample from a ovarian cancer patient who is at remission after treatment, wherein the one or more proteins are selected from the group consisting of siCAM1, sTNFR-II, RANTES, sgpl30, MMP-2, CA15-3, MIG, sVCAM-1,...
Published: 8/13/2019   |   Inventor(s): Jin-Xiong She, Ashok Sharma
Keywords(s):  
Category(s): Diagnostics
A Novel SUMO-like Gene for Type 1 Diabetes Susceptibility
Current State of the Art: Type 1 diabetes is an organ-specific autoimmune disease with aberrant immune responses to specific β-cell autoantigens. Prevention is important because diabetes interrupts normal development in children and carries the threat of severe complications in the most active period of life. Both environmental and genetic...
Published: 8/13/2019   |   Inventor(s): Jin-Xiong She, Cong-Yi Wang
Keywords(s): Diabetes II, Genomics
Category(s): Diagnostics
Sensitive Detection of Peptide Fragments Specific to Galectin-3 for the Detection and Monitoring of Well-differentiated Thyroid Cancer, Head and Neck Cancer, Lung Cancer, Colorectal Cancer and Other Cancers and Disease States
Current State of the Art:The detection of head and neck cancers, i.e. thyroid cancers, colorectal and other types of cancers are normally done via MRI or other non-specific tests. Problems with the Current Art:Such tests are not as accurate or time sensitive to identify the progression of the tumor in its early stage.Advantages of the Novel Invention:...
Published: 8/13/2019   |   Inventor(s): Paul Weinberger, John Koomen, William Dynan, David Terris, Sunny Khichi, Mark Merkley
Keywords(s): Cancer, Diagnostics, Peptides
Category(s): Diagnostics
Development of an Orthodontic Bracket Placement Device and Coordinated Bracket Placement System
Title: Orthodontic Bracket Placement Device and Coordinated Bracket Placement System Current State of the Art: Orthodontic brackets are used by general dentists and orthodontists throughout the world. The proper placement of these brackets is essential for eventual correction of poorly aligned teeth in both children and adults. In order to guide...
Published: 8/13/2019   |   Inventor(s): John Stockstill
Keywords(s): Dental, Orthodontics
Category(s): Diagnostics
Gene for Successful Aging Without Cognitive Decline
Title: Biomarker for Successful Aging without Cognitive DeclineCurrent State of the Art: It is estimated that up to one third of adults will experience a gradual decline in cognitive function known as mild cognitive impairment as they age. Individuals with cognitive decline are able to function reasonably well in everyday activities, such as managing...
Published: 8/13/2019   |   Inventor(s): Shirley Poduslo
Keywords(s): Aging, Alzheimer's Disease, Therapeutics
Category(s): Diagnostics
Portable and Non-invasive Device for the Diagnosis of Traumatic Brain Injuries
TitlePortable and Non-invasive Device for the Diagnosis of Traumatic Brain InjuriesPresent State of the ArtMild traumatic brain injuries (TBI) or concussions are diagnosed by neuropsychological tests to evaluate the cognitive functioning and basic sensory-motor processes. Problem with the Current ArtNeuropsychological testing is a lengthy and complex...
Published: 7/21/2015   |   Inventor(s): Matthew Lyon
Keywords(s):  
Category(s): Diagnostics
Protective Effects of Curcumin Against Hemorrhagic Stroke Injury
Presented here are compounds, compositions and methods for preventing and treating diseases such as intracerebral hemorrhage, cancer, or conditions associated with damaged cells, activated lymphocytes, or microbial products. The compounds are curcumin analogs. It is an object of this invention to provide compounds and compositions that have greater...
Published: 4/23/2014   |   Inventor(s): Krishnan Dhandapani, Cargill Alleyne, Mingliang Ma, Ke Wen, Wenjing Hu
Keywords(s):  
Category(s): Diagnostics
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