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Compositions and methods to increase the resistance of adoptive transfer of T cells to immunosuppression

The current state of the art: Cancer immunotherapy resurrects the patients’ suppressed immune system by increasing the immunogenicity of T cells such as the adoptive transfer of T cells (TCR and CAR T cells) and removing suppression of immune checkpoints such as PD-1/L1. Many cancer immunotherapies have been approved by the FDA. For example,...

Published: 4/7/2023 | Inventor(s): Pandelakis Koni, Esteban Celis

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Category(s): Therapeutics