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Antibody specific for PKG-1alpha nitration

Scientists at AU identified that nitration of PKG-1α in tyrosine 247 attenuates the catalytic activity of PKG-1 α, which plays a critical role in the development of vascular dysfunction in pulmonary hypertension and other vascular pathologies. The inventors developed the humanized monoclonal antibody or antigen-binding fragment for detecting...

Published: 3/31/2022 | Inventor(s): Stephen Black

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Category(s): Diagnostics, Therapeutics, Antibody