Search Results - vadivel ganapathy

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GPR81 Agonists Based Therapeutics
TitleGPR81 Agonists Based TherapeuticsCurrent State of the ArtMucosal immunity plays an important role for the prevention and cure of different pathogenic diseases.These urogenital, intestinal, and respiratory diseases are often caused by viruses, bacteria, fungi, or parasites than can diffuse through the mucosal immunity system. Different drugs ha...
Published: 8/13/2019   |   Inventor(s): Vadivel Ganapathy, Nagendra Singh, Ashish Gurav
Category(s): Therapeutics
Prodrugs of Short-Chain Fatty Acids for Treatment of Intestinal Disorders and Colon Cancer
Current State of the Art: Colon cancer, IBS, Crohn’s disease and colitis present as some of the most difficult diseases to treat with the medications available currently. Treatment can be as drastic as surgery, chemotherapy, medications, such as cortisone, which can have sometimes serious and debilitating side effects. Colon cancer is treated ...
Published: 8/13/2019   |   Inventor(s): Vadivel Ganapathy, Puttur Prasad, Robert Martindale
Keywords(s): Colon Cancer, Inflammatory Bowel Disease, Ulcerative Colitis
Category(s): Therapeutics
ATB0,+ as a Drug Target for the Treatment of Cancer, Inflammation, and Ulcerative Colitis
The current invention includes compositions having alpha methyl tryptophan, where the alpha methyl tryptophan includes the L isomer and does not include the D isomer. The alpha methyl tryptophan is used for treating cancer in patients, the method including administering to the patient to inhibit amino acid transport into cancer cells. In some aspec...
Published: 8/13/2019   |   Inventor(s): Vadivel Ganapathy, Puttur Prasad
Category(s): Therapeutics
HM74A/HM74 Ligands as Anti-Cancer and Anti-Diarrheal Drugs
Tech ID: 2007-030: Compositions Comprising a GPR109 Ligand for Treating Disorders of the Digestive Tract and/or CancerState of the Art: Top drugs for colon cancer include Xeloda (Genetech), Erbitux (Johnson and Johnson), Eloxatin (Sanofi), and Gleevec (Novartis). These four drugs ranked in the top 10 selling cancer drugs of 2011 and totaled ~$4 bil...
Published: 8/13/2019   |   Inventor(s): Vadivel Ganapathy, Puttur Prasad, Muthusamy Thangaraju, Gail Cresci
Keywords(s): Colon Cancer, Gene, Ligand
Category(s): Therapeutics
Alpha-Methyl-L-Tryptophan and Its Derivatives as Anti-Cancer Drugs
TECH IDs: 2007-020/2009-038 Title: ATBo+ as a target of Alpha-Methyl_L_Tryptophan and Its Derivatives, as Anti-Cancer Drugs and as Inhibitors of Indoleamine Dioxygenase.Current State of the Art: ATBo+, an amino acid transporter, is elevated in some breast, cervical and colon cancer cells and in intestine epithelial cells. In vivo data also support...
Published: 8/13/2019   |   Inventor(s): Vadivel Ganapathy, Muthusamy Thangaraju, Puttur Prasad
Keywords(s): Cancer, Treatment, Tryptophan Derivative, Ulcerative Colitis
Category(s): Therapeutics
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