Bioreactor for Multilayered Tissues Consisting of Different Cell Types

Description:

Title

Bioreactor for Multilayered Tissues Consisting of Different Cell Types

 

Current State of the Art

Tissue bioreactors have been pursued by surgeons and researchers for the design and production of thick tissues with potential applications in skin transplants, organ tissue (gut, bladder, trachea, etc.) replacements, etc.

 

Problem with the Current Art

Existing bioreactors produce only single type, microns thick, very fragile, small sheets of cells that often lack the desired tissue function due to the absence of complimentary cell types and may not survive in the wound bed due to its fragility.

 

Advantage of Invention

Researchers at GRU developed a full-scale prototype of the bioreactor for growing complex tissues in a scalable manner. This bioreactor chip can yield several mm tissues consisting of different cell types. Apart from tissue transplants it can also be used for high-throughput tissue engineering and pre-clinical replacement for animal models.

 

GRU #2013-043

 

Patent Information:
For Information, Contact:
Partha Choudhury
Augusta University
pchoudhury@augusta.edu
Inventors:
Paul Weinberger
Donald Mettenburg
Frederick Rueggeberg
Keywords:
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