Novel Target and New Breast Cancer Drugs for Chemo-Resistant Tumors

Description:

Researchers at AU discovered that Erbin, an ErbB2 interacting protein is necessary for the ErbB2-dependent growth of tumor cells. They prepared small peptides that disrupt the Erbin-ErbB2 interaction, increase ErbB2 degradation, and inhibit growth of tumor cells. Injection of the peptide into tumors in nude mice inhibit tumor growth. 

Patent Information:
Category(s):
Therapeutics
For Information, Contact:
Carl Clark
Director Technology Transfer
Augusta University
caclark@augusta.edu
Inventors:
Lin Mei
Wen-Cheng Xiong
Cheng-Yong Shen
Yanmei Tao
Shiwen Luo
Keywords:
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