Erbin as a Target to Regulate ErbB2 and Neuregulin Signaling

Description:

AU researchers found that erbin is a protein that interacts with ErbB2 and is critical for its expression on the surface membrane. ErbB2 becomes unstable when erbin expression is inhibited by a small interference RNA. ErbB2 is one of the most potent oncogenes in tumor genesis and metastasis. This therapeutic agent competes favorably with other drugs used to disrupt ErbB2's function.

Patent Information:
Category(s):
Therapeutics
For Information, Contact:
Carl Clark
Director Technology Transfer
Augusta University
caclark@augusta.edu
Inventors:
Lin Mei
Wen-Cheng Xiong
Yanmei Tao
Keywords:
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